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Cutaneous MALT-lymphoma: from cutaneous immunocytoma and pseudolymphoma to the current and future conceptions A.

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Fernandez-Flores The current report examines the evolution of the concepts of immunocytoma and pseudolymphoma in a historical perspective, paying special attention to their evolvement into the groups of marginal-zone lymphoma and cutaneous MALT-lymphoma.

The anatomical relations of the sphenoid sinus and their implications in sphenoid endoscopic surgery V. Budu, Carmen Aurelia Mogoanta, B.

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Fanuta, I. Bulescu Alongside the past development of endoscopic sinus surgery, knowledge about the anatomy of the sinuses has become crucial for surgeons. The sphenoid sinus is one of the most variable of all sinuses. Its relations to vital vascular and nervous elements make its approach a challenge for endoscopic surgeons.

These relations include the internal carotid artery, the optic nerve, the pituitary gland, the Vidian nerve, and other vascular and nervous elements depending on the size of the sinus.

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This paper will make a review of these anatomical relations and their importance in endoscopic sphenoid surgery. Danciu, M. Onofriescu, Cornelia Amalinei PAX8 and WT1 are transcription factors, each of them with distinct roles in organogenesis, morphogenesis, cell growth, and differentiation. Recently, their expression was also confirmed in a variety of malignancies, being included in the antibodies panel recommended for the female genital tract pathology.

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The aim of our study was to evaluate PAX8 and WT1 in different types of ovarian cancer OC with focus on i the completion of evidences of the Mullerian origin and ii the establishment of primary ovarian tumor status vs. The study group consisted of 86 cases, with histopathological diagnosis covering the main subtypes of OC low- and high-grade serous, low- and high-grade endometrioid, clear cell, mucinous, malignant Brenner tumor, malignant mixed Mullerian tumor, undifferentiated, and borderline.

The investigation was based on immunohistochemical examination, performed by using specific antibodies applied on blocks obtained through Tissue MicroArray technique, and interpreted by scores assessing the nuclear positivity of tumoral cells.

One case was not valuable due to technical difficulties. PAX8 expression was positive in 70 Our study provide ovarian cancer fast growing evidences to support the association of PAX8 and WT1 immunostaining in the investigation of the complex biology of OC, PAX8 confirming the ovarian primary and WT1 allowing the refinement of the diagnosis in phenotype overlapping cases.

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In vitro expansion and characterization of corneal stem cells isolated from an eye with malignant melanoma O. Samoila, Olga Soritau, Ovarian cancer fast growing.

Calugaru, Lacramioara Totu, S. Susman, Cristina Cristian, Carmen Mihaela Mihu Purpose: The objective of this study was the identification, characterization and in vitro replication of the human corneal stem cells, taking into consideration the difficulties in obtaining sufficient corneal material from living donors.

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The study explored a variety of stem cell markers, usually found in embryonic or adult mesenchymal stem cells. Culture medium and replication substrates had to be identified, with no data available on this subject in our country there are no other reports on corneal stem cells in Romania, to our knowledge.

Gastric cancer no symptoms - transroute. Methods The clinical gastric cancer no symptoms and therapy of patients with Helicobacter pylori infection were analyzed. The characteristic gastric cancer vegetarian the gastric cancer vegetarian between Helicobacter pylori and the mucus-epithelial cell complex, the properties of the bacterial cell components, and the inflammatory and immunological response targeting other gastric cancer vegetarian describe the immuno-pathological outbreak of Helicobacter pylori. Conclusion We support the term of toxicosis associated with Helicobacter pylori infection in selected cases. Gastric Cancer Overview - Mayo Clinic retete smoothie detoxifiant E mai posibil decât să aibă cancer la stomac.

Materials ovarian cancer fast growing Methods: Corneal epithelial limbus was harvested from an enucleated eye, containing also a choroid malignant ovarian cancer fast growing. Stem cells from the limbus were isolated and cultivated in vitro.

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Expression of specific stem cell markers was evaluated with immunocytochemistry. They also expressed pan-cytokeratin.

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Donor age medicament antihelmintic pentru oameni years and the presence of a malignant tumor close to limbal stem niche could have had an impact on the proliferation rate and the characteristics of the corneal stem cells.

Conclusions: Isolated limbal cells were adult type stem cells with an epithelial orientation. The characterization of these cells with immunocytochemistry allowed us to observe surface markers that other stem cells also express.

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Corresponding author: Ovidiu Samoila, MD; e-mail: iovidius yahoo. Development of specific tyrosine kinase inhibitors completely changed the management of these patients. Conclusions: Molecular biology techniques have an important role in monitoring CML patients and regular analysis is recommended.

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Foxp3 and IL17 expression in tumor infiltrating lymphocytes TIL and tumor cells - correlated or independent factors? Florina Vasilescu, D. Enache, Cristina Iosif, D. Alexandru, D.

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Georgescu, Camelia Dobrea, Adina Balan, Carmen Ardeleanu Tumor infiltrating lymphocytes TILas a microenvironment component were studied in various epithelial tumors, with contradictory results. Recent data about regulatory T-cells Treg revealed new explanations for pro- and anti-tumor implications of TIL.

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Tregs immunoprofile was recently completed with Foxp3 expression. A T-cell fraction Th is producing cytokine IL17 and is now considered acting in tumor progression.

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The studied material was represented by paraffin-embedded tumor fragments from 59 patients with TIL identified on HE staining. The antibodies used were Foxp3 and IL TIL was usually mild or scarce.

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A positive statistic correlation resulted between the amounts of TIL in peritumoral and intratumoral location but without correlation to histopathological grading. Tumor cells and lymphocytes Foxp3 expression was inversely correlated with the amount of TIL. In these conditions, Foxp3 could be a mediator of the tumor cells inhibitory aggression upon the immune ovarian cancer fast growing and could be used as a molecular target for biological antitumor therapy.

Histopathologic features of Spitzoid lesions in different age groups Adriana Diaconeasa, D.

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