Gastric cancer case presentation

Review of the biotechnologies and tests used for precancerous cervical lesions diagnosis Ruxandra Viorica Stanculescu, Elvira Bratila, Vasilica Bausic, Teodora Camelia Vladescu, Florina Vasilescu, Alexandra Bausic, Costin Berceanu This paper draws on the author s extensive experience in the clinical research focused on the implementation of the new biotechnologies able to identify precancerous cervical lesions and is intended to be a systematic approach to new achievements.

The goal of this review is to provide updated information concerning the significance of each biotechnology used in clinical medicine to screen women for cervical cancer or to allow a pertinent discrimination between spontaneous remission lesions and progressive lesions. The data is arranged according to the most widely used biotechnologies and the worldwide recommendations of specialized guidelines. Angiogenesis versus arteriogenesis Anna Rizzi, Vincenzo Gastric cancer case presentation, Domenico Ribatti In the vascular system, angiogenesis and arteriogenesis play a unique yet equally important role in both health and disease.

Angiogenesis, the formation of new blood vessels from a preexisting vascular bed, occurs naturally during wound healing, the female menstrual cycle and pregnancy. It plays a critical role in tissue growth and repair, and is a highly controlled process that is dependent on an intricate balance of both pro-angiogenic gastric cancer case presentation stimulate and anti-angiogenic to negatively regulate the phenomenon factors. Otherwise, the term arteriogenesis refers to anatomic transformation of preexisting arterioles with increasing lumen area and wall thickness, due to a thick muscular layer and purchasing of visco-elastic and vasomotor capacities.

Arteriogenesis differs from angiogenesis in several aspects, the most important being the dependence of angiogenesis on hypoxia and the dependence of arteriogenesis on inflammation.

Gastric cancer with ascites.

The expression of growth factors and the cooperation of surrounding and infiltrating cells seem to be essential in orchestrating the complex processes during arteriogenesis. Triple positive breast cancer - a novel category? Breast cancer has been divided in subtypes depending on the presence of hormone receptors HRs for estrogen and progesterone and human epidermal growth factor receptor 2 HER2 gene amplification.

Gastric cancer ascites.

We aim to review current evidence on this subtype of BC, from the molecular mechanisms regulating its behavior to the current standard treatment outcome in order to establish whether it qualifies as a new distinct subtype of BC. Its biology is dominated by the crosstalks between HR pathway and HER2 pathway, which might be responsible for the development gastric cancer case presentation rapid resistance to treatment, because of estrogen receptor up-regulation and alternate regulatory pathways activation when anti-HER2 agents are used.

However, most of the clinical evidence is provided by retrospective trials with multiple potential biases. Autophagy is present at a basal level in all mammals and is regulated by some conditions, such as oxidative stress, starvation or hypoxia.

In aged tissues, increased but also decreased expression of autophagy-specific proteins, Beclin 1, LC3, Atg5 and Atg7 has been reported. Likewise, it could be shown that the lifespan of yeast, nematodes and flies is prolonged by pharmacologically stimulated autophagy using exogenous administered spermidine.

Autophagy is potentially implicated in acute lung injury and sepsis, two main causes of morbidity and mortality worldwide. Finally, a quite recent study supports the hypothesis that autophagy might be useful in vascular disease prevention by stimulating cholesterol efflux, which leads to inhibition of necrotic core gastric cancer case presentation and lipid accumulation.

Gastric cancer with ascites

However, cases of regression have been reported. Recent reviews cover only certain aspects of this disease; therefore, this paper s aim is to cover all the relevant aspects for medical practice, such as clinical, histological and therapeutic details.

BD may affect all regions of the skin and mucosa, but in accordance with the region and etiologic factor, it may embrace different clinical forms, some of them very similar with other skin lesions. Dermoscopy may prove useful for establishing a clinical diagnosis. Several patterns have been encountered and may help distinguishing from other diseases. When in doubt, puncture biopsy or complete excision may be performed in order to obtain histological data that could define BD.

Keynote Lecture: Hereditary aspects of gastric cancer

Different morphological aspects of the involved components are described in order to reduce the risk of misdiagnose. In order for the approach to be complete, relevant information about treatment has been presented, underlining the pros and cons of each available therapy.

A systematic review of the possible carcinogenic role of the aristolochic acid Tivadar Bara Jr. AA is also shown to be involved in the genesis of the upper urinary tract urothelial carcinoma UTUC and some other cancers, but its tumorigenic role is far to be understood.

We performed a systematic literature review regarding the involvement of AA in malignant processes and molecular pathways of carcinogenesis. Twenty representative papers were selected for this review. These papers reveal that AA exposure increases the risk for UTUC, renal cell carcinoma, hepatocellular carcinoma, gastric and small intestine cancer. The role of AA in lymphomagenesis is also proposed.

• Abstract Multiple primary tumors can be synchronous when detected simultaneously or metachronous when detected after a variable time interval.
• Cornelia Nitipir - Google Scholar Citations
• Gastric cancer case presentation, Gastric cancer facts

For further understanding of AA s role in tumorigenesis, the exploration of the AA s molecular signature is necessary. The ultraviolet influence upon soft eye tissues Sanda Jurja, Malina Coman, Mihaela-Cezarina Hincu The climate changes, which occurred during the last decades, put all living species in front of new challenges. Human biology is no exception to it, all tissues have to face new effects, with unpredictable consequences. Many cancers, mainly affecting the skin, but also many of the eye various structures diseases, have ultraviolet radiation as recognized causative agent.

The aim of our work is to highlight the changes that can occur after exposure to ultraviolet radiations of soft tissues, including eye structures, by reviewing data from the scientific literature regarding the matter.

Responsible for gastric cancer case presentation diseases, including cancer, ultraviolet negative effects on various soft tissues can be limited by better comprehension.

Their knowledge gastric cancer case presentation contribute to improving public health, by finding new preventive methods, which might represent the foundation of effective public health programs.

Role of genetic polymorphism in nutritional supplementation therapy in personalized medicine Nicolae Ovidiu Penes, Bernard Weber, Silviu Dumitru Paun Genetic-guided nutritional supplementation therapy in personalized medicine is gastric cancer case presentation type of treatment that prevents and acts against errors during the copying process of a cell s deoxyribonucleic acid DNAmistakes that lead to diversification in the DNA sequence at certain locations, called single nucleotide polymorphisms SNPs.

Positive results are quickly achieved using one of the four types of therapy. These types are: personalized, when individual human genetic variations drive individual treatment, preventive, with a tailored healthcare strategy and therapeutic preventive drugs and vaccines, participatory, when empowered patients make informed choices and take responsibility of their own health and predictive, using a proactive approach to health and medicamente pentru tratamentul papilomului Preț. Three-dimensional organ scanning reveals brain edema reduction in a rat model of stroke treated with an aquaporin 4 inhibitor Elena Silvia Popescu, Ionica Pirici, Raluca Niculina Ciurea, Tudor-Adrian Balseanu, Bogdan Catalin, Claudiu Margaritescu, Laurentiu Mogoanta, Sorin Hostiuc, Daniel Pirici Stroke is one of the most important cause of death and disability, especially when considering the increasing life expectancy worldwide, with ischemic stroke being much more common than hemorrhages.

1. Assoc. Prof. Simona Muresan – Team UMCH
2. Condilom la femeile din anus
3. METACHRONOUS LUNG CANCER - CASE PRESENTATION | The Medical-Surgical Journal
4. Ce copii sunt folosiți pentru tratarea viermilor?
5. The endometrial regeneration frontiers: from mechanisms to applications in regenerative medicine Cornelia Amalinei, Ioana Pavaleanu, Adriana Grigoras, Irina-Draga Caruntu, Simona Eliza Giusca, Elena Roxana Avadanei, Ludmila Lozneanu, Raluca Anca Balan The endometrium is a unique and remarkable tissue characterized by a constant regeneration activity and this has been speculative for scientists, regarding its mechanism, regulatory factors, and their significance for fertility and endometrial pathology.

In the physiopathological chain of ischemic gastric cancer case presentation, brain edema is one first element that if attended to might reduce tissue necrosis, penumbra, and increase functional recovery. Aquaporin 4 AQP4 has been found to be the most important water channel in the brain, and its inhibition before inducing focal ischemia in an animal model of stroke proved to alleviate the pathology and improve clinical recovery.

In this study, we have treated a rat model of ischemic stroke with the AQP4 inhibitor TGN after inducing the lesion, and performed for the first time a direct histopathological evaluation of the brain and infarct s volume. Besides utilizing immunohistochemistry targeting the growth-associated protein GAP in order to delineate the infarct regions, we have used the Cavalieri s principle of tissue volume measurements starting form seriate sections, and for the first time in neuropathology, we have utilized a high-resolution gastric cancer case presentation scanner to assess global brain volume changes.

Our results showed that TGN clearly reduces infarct volume in TGN treated animals compared to untreated animals, as well as gastric cancer case presentation volume of the brain hemispheres.

Although reduced, the effect was also present in the contralateral hemisphere. Given these data, a more in-depth characterization of the histopathological and molecular changes induced by AQP-4 are needed for considering it as a bona fide treatment option.

Prenatal glucocorticoid administration persistently increased the immunohistochemical expression of type-1 metabotropic glutamate receptor and Purkinje cell dendritic growth in the cerebellar cortex of the rat Rodrigo Pascual, Odra Santander, Isabel Cuevas, Martina Valencia Several studies have indicated that abnormal prenatal changes in the circulating glucocorticoids GCsinduced by either maternal stress or exogenous GC administration, significantly alter the development of Purkinje cells PCs.

Among the suggested mechanisms that could mediate this GC-dependent PC susceptibility are changes in the expression of type-1 metabotropic glutamate receptors mGluR1.

Aggressive variants of prostate cancer - Are we ready to apply specific treatment right now? Cancer Treat Rev. In most cases, prostate cancer essentially depends on androgen receptor signaling axis, even in castration-resistant setting, and hence may be targeted by second generation hormonal therapy. However, a subset of patients bears androgen-independent cancer biology with a short-term response to hormonal treatment, early and extensive visceral metastases, low PSA levels and poor outcomes.

In the current study, we analyzed whether a single course of prenatally administered betamethasone phosphate BET in pregnant rats increased the immunohistochemical expression gastric cancer case presentation mGluR1 in PCs and decreased PC dendritic growth. The data obtained showed that in utero BET exposure resulted in a significant immunohistochemical overexpression of mGluR1 and a significant reduction in Purkinje cell dendritic outgrowth during postnatal life.

Large variability of the activity and chronicity indexes within and between histological classes of lupus nephritis Tudor Azoicai, Ioana Madalina Belibou, Ludmila Lozneanu, Simona Eliza Giusca, Elena Cojocaru, Irina-Draga Caruntu Systemic lupus erythematosus SLE is characterized by a multifaceted pathogenesis and a heterogeneous clinical expression.

The present study aimed to reevaluate a series of cases diagnosed as LN, focusing on the histological features in correlation with the level of activity and chronicity.

Simona Silviana Muresan

The study group comprised 46 patients. The specimens obtained through percutaneous needle biopsies were processed for light microscopy and immunofluorescence exams. In 39 out of the total of 46 The differences in diagnosis were present in seven cases, initially considered as pure membranous glomerulonephritis - class V. The values of indexes indicated a great variability of LN within the same class.

Gastric cancer facts,

The interobserver agreement for the scoring of activity gastric cancer case presentation chronicity indexes was 0. Our study cum se elimină papiloamele în locuri intime the complex lesion character, which requires an individual and accurate identification, followed by integration in the classification algorithm used to define the classes and subclasses of LN diagnosis.

The degree of activity and chronicity in SLE must be refined through a much more precise correspondence between the score value and the limitation or extension of corpuscular and interstitial lesions. Rapid on-site examination ROSE is a rapid, real-time examination method. The aim of our study is to evaluate the impact of ROSE on adequate specimen sampling, rapid results and high diagnostic rate.

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We evaluated the diagnostic capacity of ROSE for malignant tumors, by considering the histopathological examination as the diagnostic gold standard. In our retrospective and descriptive study, we analyze the data of EBUS-TBNA examinations with ROSE and histopathological exam, performed for diagnostic purposes for hilar and mediastinal adenopathies of unknown origin.

The age of the patients varied from 21 to 80 years, with an average age of There were 98 male patients, representing The sensitivity of the ROSE is This brings a valuable contribution to the improvement of lung cancer diagnostic. The present paper aimed to define the profile of SCC of the lip with major risk factors. The study included 20 selected cases diagnosed with lower lip SCC, using a panel of antibodies which addressed cell proliferation Ki67perturbation of gastric cancer case presentation cell Gardia provoacă diaree sângeroasă p53angiogenesis VEGF - vascular endothelial growth factorfactors related to tumor cell interaction with the extracellular matrix CD Ki67 immunoexpression was identified in all the cases.

We found significantly higher mean values of Ki67 PI in pT3 lesion, compared with pT2 and pT lesions, and with no statistically significant differences in lip SCC with associated lymph node metastasis pN1compared to those with no lymph node metastasis pN0. Immunohistochemical investigations in lip SCC, regarding the expression of p53, Ki67, CD44 and VEGF, revealed results that suggest their ability to assess the prognosis and progression of tumor evolution.

Optical coherence tomography applications in gastric cancer case presentation wear diagnosis Veronica Mercut, Sanda Mihaela Popescu, Monica Scrieciu, Marina Olimpia Amarascu, Mihaela Vatu, Oana Andreea Diaconu, Eugen Osiac, Stefan Mugurel Ghelase Dental wear represents an irreversible loss of dental hard tissue under the action of physical, chemical and mechanical factors, excluding dental caries and acute trauma.

It is important to distinguish between primary ovarian cancer and metastatic tumors in the ovary because their management is different, in terms of treatment and follow-up. We report the perioperative management of a year-old female patient with bilateral Krukenberg tumors. Este important să se facă distincţia între cancerul ovarian primar şi tumorile metastatice ale ovarului, deoarece managementul lor este diferit în ceea ce priveşte tratamentul şi urmărirea. Raportăm managementul perioperator al unei paciente de 40 de ani, cu tumori bilaterale Krukenberg. Cuvinte cheie tumora Krukenberg cancer gastric imunohistochimie Introduction Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potential and being subclassified into several categories based on two criteria: the degree of epithelial proliferation and invasion and the histotype of the epithelium composing the tumors 1.

Gastric cancer case presentation clinical forms of dental wear are described: erosion, attrition, abfraction, and abrasion. Most experts agree that in each clinical form multiple etiological factors gastric cancer case presentation involved, one being predominant. Optical coherence tomography OCT is a non-invasive optical method characterized by a micronic resolution.